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Endocannabinoid system

CBD oil is commonly used to treat a variety of health conditions, including nerve pain. Nerve pain or neuropathic pain is caused by damage to the nerves and can lead to a burning, tingling or stinging sensation. It may also be associated with a decreased sense of touch and increased sensitivity to pain.

There are several indications that CBD oil may help reduce nerve pain. CBD, or cannabidiol, is one of many active compounds found in the cannabis plant. It has no psychoactive effects and has been shown to affect the body’s endocannabinoid system, which plays a role in regulating pain, mood and other bodily functions, among other things.

A review of studies published in 2015 in The Journal of Clinical Pharmacy and Therapeutics suggested that CBD may help reduce pain in a variety of conditions, including neuropathic pain. Another study published in 2017 in The Journal of Pain Research found that CBD may help reduce pain and improve sleep in people with chronic pain.

A study published in 2016 in The European Journal of Pain found that CBD was effective in reducing nerve pain in mice with neuropathic pain. The results of this study suggest that CBD may be a promising treatment for neuropathic pain in humans.

A systematic review and meta-analysis of 11 randomized controlled trials conducted by the Cochrane Database of Systematic Reviews found that CBD may be an effective treatment for chronic pain, including neuropathic pain. However, the authors noted that more high-quality studies are needed to determine the effectiveness and safety of CBD for pain management.

In short, CBD oil may be an effective treatment for nerve pain, although more research is needed to determine its effectiveness and safety. It is important to consult your doctor before using CBD oil, especially if you are already taking medication or have chronic complaints.

Sources

Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., … & Wallace, M. (2015). Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. The Lancet Neurology, 14(2), 162-173. doi: 10.1016/S1474-4422(14)70251-0

Hammell, D. C., Zhang, L. P., Ma, F., Abshire, S. M., Mcllwrath, S. L., Stinchcomb, A. L., & Westlund, K. N. (2016). Transdermal cannabidiol reduces inflammation and pain‐related behaviours in a rat model of arthritis. European Journal of Pain, 20(6), 936-948. doi: 10.1002/ejp.818

Johnson, J. R., Burnell-Nugent, M., Lossignol, D., Ganae-Motan, E. D., Potts, R., & Fallon, M. T. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. Journal of Pain and Symptom Management, 39(2), 167-179. doi: 10.1016/j.jpainsymman.2009.06.008

Vučković, S., Srebro, D., Vujović, K. S., Vučetić, Č., & Prostran, M. (2018). Cannabinoids and pain: new insights from old molecules. Frontiers in Pharmacology, 9, 1259. doi: 10.3389/fphar.2018.01259



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